三七總皂苷及其制劑用于“全身炎性反應綜合征”輔助治療的用途制造技術

本發明專利技術涉及三七總皂苷及其制劑用于“全身炎性反應綜合征”(SIRS)輔助治療的用途。針對SIRS的啟動因子-內毒素，對其進行有效清除。針對SIRS發展過程中的主要損傷因素-炎性介質，對其進行抑制。針對由內毒素所造成肺、肝臟、腎臟、小腸等重要臟器的損傷有進行有效防治。對抗由內毒素造成的血管內皮細胞損傷，保護血管內皮細胞。改善在SIRS病理狀態下的嚴重循環障礙，增加微循環血流量，從而發揮對SIRS的輔助治療作用。

Use of total saponin 37 and its preparation for adjuvant treatment of systemic inflammatory response syndrome

The present invention relates to the use of 37 total saponins and their preparations for the adjuvant treatment of systemic inflammatory response syndrome (SIRS). The endotoxin, which is the promoter of SIRS, is removed effectively. The main injury factors, inflammatory mediators, are suppressed in the development of SIRS. Effective prevention and treatment of the lung, liver, kidney, small intestine and other important organs caused by endotoxin are effective. Against the injury of vascular endothelial cells caused by endotoxin, and protect the vascular endothelial cells. To improve the severe circulatory disturbance under SIRS pathological condition, and to increase the microcirculation blood flow, so as to play an auxiliary role in the treatment of SIRS.

【技術實現步驟摘要】

【技術保護點】
１．三七總皂苷或其制劑在制備用于治療或輔助治療內毒素所致的血管內皮損傷、肺損傷、肝損傷、腎損傷、或出血性壞死性腸炎的藥物中的用途。

【技術特征摘要】

【專利技術屬性】
技術研發人員：普俊學，馬維鵬，吳瓊粉，
申請(專利權)人：昆明制藥集團股份有限公司，
類型：發明
國別省市：53